417. Induction of Potent Cytotoxic and Antitumor Activity By a Highly Optimized hTERT DNA Vaccine
نویسندگان
چکیده
منابع مشابه
Highly optimized DNA vaccine targeting human telomerase reverse transcriptase stimulates potent antitumor immunity.
High levels of human telomerase reverse transcriptase (hTERT) are detected in more than 85% of human cancers. Immunologic analysis supports that hTERT is a widely applicable target recognized by T cells and can be potentially studied as a broad cancer immunotherapeutic, or a unique line of defense against tumor recurrence. There remains an urgent need to develop more potent hTERT vaccines. Here...
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15 صفحه اولPotent Antitumor Activity Generated by a Novel Tumor Specific Cytotoxic T Cell
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ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2015
ISSN: 1525-0016
DOI: 10.1016/s1525-0016(16)34026-6